The global stock market is currently operating in an environment full of economic uncertainty, triggered by various factors ranging from rising inflation, changes in monetary policy, to geopolitical turmoil. In this situation, investors must be careful and strategic in order to manage risks while looking for opportunities amidst uncertainty. Inflation is one of the main factors influencing stock market movements. When inflation rises, central banks in various countries tend to raise interest rates to stabilize the economy. This increase has a direct impact on borrowing costs, which can suppress the company’s profitability. Investors need to pay attention to sectors that have the potential to be more resistant to inflation, such as the health sector and consumption of staples, which tend to be stable in volatile economic situations. Apart from inflation, changes in monetary policy also contribute to market uncertainty. For example, a policy reversal of extensive monetary stimulus could cause stock markets to experience volatility. When investors start to become defensive, stocks previously considered ‘blue chips’ may experience a reduction in demand, causing prices to fall. Skills in analyzing economic data and financial reports are important for investors who want to determine the right shares to buy or sell. Geopolitical turmoil, such as international conflicts and trade tensions, also play a role in creating uncertainty. For example, tensions between the United States and China impact many companies with global supply chains. This uncertainty can cause fluctuations in technology stocks, as seen with large companies that depend on the accessibility of the Chinese market. Investors must always have updated information regarding geopolitical developments to help make more informed investment decisions. The importance of portfolio diversification is increasing in these uncertain market conditions. Investors are advised to spread their investments across different assets and sectors to reduce risk. As uncertainty increases, safe haven assets such as gold and government bonds are often sought as a means of protection. Combining these assets with stocks that are expected to provide long-term growth can create a healthy balance in a portfolio. In addition, investors need to use technical and fundamental analysis to monitor market trends. Understanding price movement patterns and technical indicators can help investors identify the right moment to enter or exit the market. Fundamental analysis which includes assessing company performance and growth estimates is the key to making wise investment decisions. The existence of economic uncertainty is not completely negative; it also creates new investment opportunities. Innovative sectors such as sustainable technology and digital health, continue to thrive despite difficult market conditions. Therefore, smart investors must keep their eyes open to new trends and adapt to rapid market changes. With all this, global stock markets face significant challenges, and a deep understanding of the factors influencing the market will determine investment success amidst economic uncertainty. Success in this market depends not only on luck, but also on knowledge and a good strategy for dealing with it.